The charming capital city of Nueva Gerona is just a tiny town, with only about 50,000 inhabitants, filled with the historic architecture and the vintage American cars that make Cuba famous.
The most famous nearby key is Cayo Largo del Sur, home to Playa Paraiso and Playa Sirena, which is largely considered the most beautiful beach in Cuba.
Isla de la Juventud is easily accessible by regular flights from Havana, so you can add a day in Old Havana to your itinerary before catching a flight to Nueva Gerona.